World number one Serena Williams, trying to complete a calendar-year Grand Slam at the US Open, could face sister Venus in the quarter-finals and Maria Sharapova in the semi-finals.

The draw conducted Thursday at Arthur Ashe Stadium set the path for Williams to try and make more tennis history as she seeks a 22nd career Grand Slam singles crown to match the Open Era record total of Steffi Graf.

Williams will open against Russia's Vitalia Diatchenko and could face Croatian Mirjana Lucic-Baroni in the second round.

Poland's Agnieszka Radwanska, seeded 15th, is a possible round of 16 foe for Williams, with her elder sister or Swiss teen Belinda Bencic -- who beat Williams in the Toronto semi-finals earlier this month -- possible quarter-final opponents.

Sharapova is in Williams' half of the draw as well with Romania's second-seeded Simona Halep or Danish fourth seed Caroline Wozniacki her highest-rated potential finals foes.
Source: AFP