World number one and reigning Australian Open and Wimbledon champion Novak Djokovic was confirmed on Wednesday as top seed in the men’s singles at the US Open which starts on Monday. Djokovic, a three-time Grand Slam champion, but who is seeking his first US Open title, is the No. 1 seed at the tournament for the first time. He will be followed by No. 2 Rafael Nadal, the defending champion; No. 3 Roger Federer of Switzerland, a five-time US Open winner and No. 4 Andy Murray of Great Britain, the 2008 runner-up. Djokovic holds a 57-2 record leading up to this year’s US Open. He has won nine titles this year, including five Masters events, along with his second Australian Open and first Wimbledon titles. The Serbian is a two-time US Open runner-up, losing to Nadal last year and to Federer in 2007. For the first time in his career, Mardy Fish will be the highest-seeded American at No. 8 with 2003 champion Andy Roddick seeded at 21. The draw for the final Grand Slam event of the season takes place on Thursday. Seeds: Men's singles 1. Novak Djokovic (SRB), 2. Rafael Nadal (ESP), 3. Roger Federer (SUI), 4. Andy Murray (GBR), 5. David Ferrer (ESP), 6. Robin Soderling (SWE), 7. Gael Monfils (FRA), 8. Mardy Fish (USA), 9. Tomas Berdych (CZE), 10. Nicolas Almagro (ESP), 11. Jo-Wilfried Tsonga (FRA), 12. Gilles Simon (FRA), 13. Richard Gasquet (FRA), 14. Stanislas Wawrinka (SUI), 15. Viktor Troicki (SRB), 16. Mikhail Youzhny (RUS), 17. Jurgen Melzer (AUT), 18. Juan Martin Del Potro (ARG), 19. Fernando Verdasco (ESP), 20. Janko Tipsarevic (SRB), 21. Andy Roddick (USA), 22. Alexandr Dolgopolov (UKR), 23. Radek Stepanek (CZE), 24. Juan Ignacio Chela (ARG), 25. Feliciano Lopez (ESP), 26. Florian Mayer (GER), 27. Marin Cilic (CRO), 28. John Isner (USA), 29. Michael Llodra (FRA), 30. Ivan Ljubicic (CRO), 31. Marcel Granollers (ESP), 32. Ivan Dodig (CRO) Women's singles 1. Caroline Wozniacki (DEN), 2. Vera Zvonareva (RUS), 3. Maria Sharapova (RUS), 4. Victoria Azarenka (BLR), 5. Petra Kvitova (CZE), 6. Li Na (CHN), 7. Francesca Schiavone (ITA), 8. Marion Bartoli (FRA), 9. Samantha Stosur (AUS), 10. Andrea Petkovic (GER), 11. Jelena Jankovic (SRB), 12. Agnieszka Radwanska (POL), 13. Peng Shuai (CHN), 14. Dominika Cibulkova (SVK), 15. Svetlana Kuznetsova (RUS), 16. Ana Ivanovic (SRB), 17. Anastasia Pavlyuchenkova (RUS), 18. Roberta Vinci (ITA), 19. Julia Goerges (GER), 20. Yanina Wickmayer (BEL), 21. Daniela Hantuchova (SVK), 22. Sabine Lisicki (GER), 23. Shahar Peer (ISR), 24. Nadia Petrova (RUS), 25. Maria Kirilenko (RUS), 26. Flavia Pennetta (ITA), 27. Lucie Safarova (CZE), 28. Serena Williams (USA), 29. Jarmila Gajdosova (AUS), 30. Anabel Medina Garrigues (ESP), 31. Kaia Kanepi (EST), 32. Maria Jose Martinez Sanchez (ESP).