It is yet another must-win game for the Blaugrana, who cannot afford to drop any more points if they wish to retain hope of lifting a fourth straight La Liga title.Pep Guardiola is set to make changes as Barcelona prepare for their second game in the space of three days by taking on Getafe at Camp Nou on Tuesday.Xavi, Andres Iniesta and Sergio Busquets could all return to the starting XI after the trio were rested on the bench for Saturday\'s win at Zaragoza, while Gerard Pique, who missed the trip to Aragon with a thigh strain, remains a doubt.Winger Ibrahim Afellay is nearing full fitness, but is not expected to be involved in the clash.Getafe defender Mane is unavailable after receiving his fifth yellow card of the season in the weekend victory over Sporting Gijon.Abdelaziz Barrada may return to the starting line-up after overcoming a muscular problem, while Pedro Leon (knee) could also feature.